Not too long ago, regulations on CBD changed in Germany leading to a plethora of products containing it. As someone who occasionally needs pain medication, I tried some of the products to avoid regular pain killers (ibu). Especially on days with lighter pain, I wished for an alternative to the sledgehammer meds. But I was left standing in the rain. I didn’t feel any effect. That’s why I would love to hear from your experiments and experience.

  • cerement@slrpnk.net
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    1 year ago

    the problem is the legality of other cannibinoids where you live …

    • from the states in the US where cannabis has been legalized – neither CBD nor THC will show their full effects in isolation, they each help to augment the other – so even something like a tiny amount of THC added to CBD (ex. 20:1 CBD to THC) will drastically enhance the CBD effects
    • there are two primary (and a lot of secondary) pain systems within the body – one of them responds better to opioids, the other responds better to cannibinoids cannabinoids – everyone’s different and responds differently so it requires a knowledgeable medical professional who hasn’t bought into US’s “reefer madness” propaganda that’s been foisted off onto the rest of the world
    • Eladarling@lemmy.world
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      1 year ago

      I’m in bed with a fractured wrist and an opoid intolerance/allergy. Where can I learn more about the dominant pain systems/different solutions you mentioned?

      • cerement@slrpnk.net
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        1 year ago

        proviso: I am not medically trained and most of what I’ve picked up has been informally through the American cannabis communities and legalization efforts

        and options for dealing with pain in the US are a hot topic item – you need a medical professional that is knowledgeable about ALL the options but doctors get their licensing at the federal level, not the state level, so they risk their license to even talk about cannabis

        from what I’ve stumbled across, opioids work better on acute pain (ex. fractures) and cannabinoids work better on chronic pain (ex. fibromyalgia, stress) – ie. cannabis will help with aches and tension, allowing you to get a night’s sleep – but for direct pain from the fracture, you might be stuck with NSAIDs which have their own slew of issues

        I know almost nothing about the other pain systems, but Wikipedia generally has some good starting points

        • cannabinoid
          • “Before the 1980s, cannabinoids were speculated to produce their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in animals. Two known cannabinoid receptors are termed CB1 and CB2, with mounting evidence of more. The human brain has more cannabinoid receptors than any other G protein-coupled receptor (GPCR) type.”
        • endocannabinoid system
          • “The Endocannabinoid System (ECS) regulates many functions of the human body. The ECS plays an important role in multiple aspects of neural functions, including the control of movement and motor coordination, learning and memory, emotion and motivation, addictive-like behavior and pain modulation, among others.”
          • CB1 receptor
          • CB2 receptor
    • FUsername@feddit.deOP
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      1 year ago

      Thank you for your balanced thoughts! Well your first point kinda might be an issue. I guess I haven’t dived deep enough into this topic to answer whether these mixtures are legally available here. Speaking of it: can you (or someone you know 😉) feel any psychedelic effect of the THC with a 20:1 ratio?

      I tried to convince trained professionals twice to go the mentioned route with me. Instead, the looked for me as if I asked for a roofie on the house. So that is another issue…

      • cerement@slrpnk.net
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        1 year ago
        • most people (depending on tolerance) don’t notice much psychoactive effect from THC below ~5mg
        • from Wikipedia, it looks like in Germany you have to get a medical pass to get access to whole cannabis or THC
        • you will get a similar reaction from doctors in the US
          • in the US, doctors are licensed at the federal level, cannabis is legalized at the state level – doctors risk their license even talking about cannabis regardless of its legality in the state they operate in – no trained professional is going to risk their livelihood
          • most of the world is still victim of the US’s “reefer madness” propaganda campaign (thanks to Nixon and his “War on Drugs”) and it still bears the stigma of “the devil’s weed” – so, unless you find someone knowledgeable, you can expect the attitude of “asking for a roofie” to be the standard response