cross-posted from: https://lemmy.ca/post/39850196

It involves removing a patient’s tooth, usually the canine, installing a plastic optical lens inside it, and then implanting the whole thing into the eye.

  • Salamander@mander.xyz
    2·
    10 hours ago

    Thanks a lot for looking into this!

    While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.

    I am not super familiar with the topic, but I have been told of some successful animal studies on implanting the organoid tissue into the animals from which the stem cells were derived.

    This other article from 2013 lists a few concerns, and I think this is the closest to what you were looking for: https://pmc.ncbi.nlm.nih.gov/articles/PMC3931018/#sec3

    Yeah, that covers nicely what I was wondering about. Especially the reason 1 (embryonic proteins not present during immune system education) and reason 2 (epigenetic changes). I can appreciate that these mechanisms might possibly cause issues, but I would be curious to learn the actual magnitude of their impact.

    Yamanaka named iPSCs with a lower case “i” due to the popularity of the iPod and other products.

    Oooh, that’s why! I do think iPSC looks nicer than IPSC. Not a big apple fan, though